Irene Saxby
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Articles
Recent activity by Irene Saxby-
How to make a Custom Antibody Reference Database
As a user of Biologics, you can make your own custom Reference Databases for annotating your sequences. For more detail on what a custom reference database is, please see this article: Understandin...
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NGS Antibody Annotator
If you have datasets larger than 5 million sequences, we recommend using NGS Antibody Annotator. The NGS Antibody Annotator pipeline uses an alternative algorithm to Antibody Annotator that collaps...
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Analyzing TCR sequences in Geneious Biologics
Although initially designed to annotate IgG and BCR sequences, Geneious Biologics can aIso annotate TCR variable regions. All that is needed for this is a correctly formatted Reference Database con...
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Workflows and Flowcharts for Antibody Analysis
This article outlines the general workflow through the Biologics platform to analyze your variable region antibody and antibody-like sequences. It serves as a general guide and does not include all...
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Quick Analysis
This article outlines how to use Quick Analysis, a simple tool to annotate and visualize your sequences with as little analysis customization as possible. Quick Analysis is available as part of the...
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Clustering options
This article outlines the different options available for creating custom clusters when using the Antibody Annotator, NGS Antibody Annotator or Single Cell Antibody Analysis tool. If you are unsure...
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Deleting Documents and Results
When deleting any item in Geneious Biologics it will be scheduled for deletion in 30 days. This article outlines how to delete documents (results, sequences, folders etc.) and how to restore docume...
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NGS Antibody Analysis: All Sequences Table Columns
This article lists each column in the All Sequences Table produced by a typical NGS Antibody Annotator run, and what each column represents. If you want to learn more about the columns of a cluster...
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General Template Databases
General Template databases can be used with our Peptide Annotator, which is used to annotate and cluster protein and peptide sequences. If you are unsure what a reference database is, see Understan...
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NGS Tutorial 1. Sequence Analysis
It is advisable to read the Quick Start Guide to help you get familiarised with Geneious Biologics before proceeding with the following tutorial. NOTE: A previous version of this tutorial using An...