Megan Kennington
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November 2020 - Searchable Collections
While world events unfold outside our bubbles, the Geneious Biologics team has been hard at work finishing our new Collections feature, which is now available for everyone. Searchable Collections...
What is a Collection?
Collections are a way of saving curated lists of annotated antibody sequences, complete with assay data and other relevant sequence information. Collections can be searched against to find any sequ...
Can I adjust my CDR definitions?
There are three different ways to adjust the way Antibody Annotator and other pipelines identify the boundaries between FR and CDR regions. "Result Annotation Scheme" is the best option when using ...
July 2020 - Multi-region Alignment
I hope everyone is safe and well. I just wanted to let you know about our latest (and much anticipated) alignment improvement in Geneious Biologics. You can now align multiple regions at once, dire...
June 2020 - Dynamic Reporting, Automated Sequence Repair, and more
Here at Geneious Biologics we are still working from home, but we may soon return to the office depending on what the New Zealand government recommends. We have been busy and have recently released...
How do I merge overlapping fragments of a DNA sequence into a longer contig?
Assembly is normally used to align and merge overlapping fragments of a DNA sequenceto reconstruct the original sequence. The assembly essentially appears as a multiple sequencealignment of reads (...
Users and Groups
Geneious Biologics works best if each user in your organisation has a separate login. This allows each user to keep private folders, and view the jobs they have run. It also allows users to have th...
Collapse UMI Duplicates and Separate Barcodes
What is the Collapse UMI Duplicates and Separate Barcodes operation? Depending on sequencing platform and laboratory preparation, your sequences may have adapters, barcodes, unique molecular identi...
Can I add custom sequence liabilities and assets with their associated scores?
The Antibody annotator has a default set of sequence liability checks. These include cleavage, deamidation, glycosylation, hydrolysis, isomerization, and oxidation. These can be selected by checkin...
How do I group standalone sequences?
Sequence lists make it easier to manage large numbers of sequences by grouping related sequences into a single document. To group standalone sequences or multiple sequences lists into a sequence l...